In Mycelium: Descubriendo el reino fungi ("Discovering the Fungi Kingdom"), we'll participate in all fundamental stages of a fungus' life cycle, from a small spore floating in the air to the creation of the first mycelium, which will grow and feed from substrates. Once the environmental conditions are favorable, they'll manifest in the form of mushrooms to restart their cycle.

Each player places their spore token on the board and starts spreading their mycelia, placing hex tiles through the forest to build a mycelial network to get nutrients either from substratum tokens scattered all around or by making symbiosis with the trees to gain bonus nutrients during play.

The game can be played competitively or co-operatively, with the goal in the latter set-up being to reach a certain point total against one of three difficulty levels. A 2v2 team-game mode is also available. In a competitive game, the first player or team to reach the respective point goal wins.