Milan, early 20th century, the city is in turmoil as more than 200 new buildings are rushed to being completed in time for welcoming the best minds of the planet. The 1906 Universal Exposition is approaching and, as one of the 40 exhibiting nations, you are confident that your engineers and scientists will impress the world. Who will exhibit the most impressive technological advancements? Which energy source will prevail: the majestic power of Steam or the more elegant and efficient Electricity? Can you prevail in prestige and glory against the other competing nations?

In Expo 1906, players will win by totaling more prestige points at the end of the game than their opponents. Points are awarded for completing Projects which represent historical inventions of the period. To complete a Project, a player must purchase Resources and place them in a proper combinations together with a Project in his Laboratory. This is a challenging task as Projects come in many different shapes and must fit together with their resources in an already tight space. Soon the available room in the Laboratory will reduce and players will face the puzzle solving aspect of the game.

Strategy plays an important role too: to speed up the completion of a Project players can acquire Technologies, which can either reduce the number of Resources required to complete a Project or enhance the type of actions at their disposal. This will require careful management of the available space in their Laboratory too. Also, by registering ideas at the Patents'Office players can become leader in the development of specific Resources and accumulate more prestige points when completing Projects. Setting priorities between all these actions will become critical as players rush to prepare in time for the upcoming World Exposition.